FDA-approved genericAbout 10 minutes, online.
A US-licensed physician decides.
Ships discreetly from a US-licensed pharmacy.
Tretinoin Cream
Prescribed by a US physician · Dispensed by a licensed US pharmacy
Tretinoin cream is a prescription retinoid (stronger than over-the-counter retinol) used for acne and, over months of use, to improve skin texture, dark spots, and fine lines. Your physician chooses your strength, tretinoin 0.025%, 0.05%, or 0.1%, and how to build up from a few nights a week. Ships as a 45 g tube, ...
Tretinoin cream is a prescription retinoid (stronger than over-the-counter retinol) used for acne and, over months of use, to improve skin texture, dark spots, and fine lines.
Your physician chooses your strength, tretinoin 0.025%, 0.05%, or 0.1%, and how to build up from a few nights a week. Ships as a 45 g tube, billed every 3 months, with your tretinoin prescription handled online.
Expect dryness, peeling, or irritation in the first weeks as your skin adjusts, and wear sunscreen daily while you use it.
Prescription required. A licensed physician decides if tretinoin is right for you.
Prescription only. A licensed physician decides eligibility from your medical intake. Individual results vary.
HOW IT WORKS
What happens after you start?
You won't be charged unless a licensed physician approves you.
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Today
Start your protocol
Pick your strength and check out. Your medical intake opens right after.
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About 10 minutes
Complete your intake
Answer the medical questions online. No appointment, no waiting room.
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Typically within a few days
Physician review
A US-licensed physician reviews your intake and decides whether this protocol is appropriate for you. If it isn't, the hold on your card is released and you're not charged.
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Ongoing
Fulfilled & delivered
If approved, a US-licensed pharmacy fulfills your prescription and ships it to your door on your plan's schedule.
One price
Everything in the price.
- US-licensed physician review. Visits elsewhere run $49–79.
- Your medication. From a US-licensed pharmacy.
- Free discreet shipping.
- Unlimited physician messaging during treatment.
- Price lock. Your price never goes up.
Plus
- A routine card in the box
- A 90-day physician check-in
THE SCIENCE
How does Tretinoin Cream work, and what does it cost?
Tretinoin is a topical retinoid that accelerates skin cell turnover, unclogs pores, and stimulates collagen, improving acne, texture, and fine lines over time. Expect dryness, peeling, redness, and increased sun sensitivity, especially in the first weeks. Not for use in pregnancy.
FACT SHEET
WHAT TO EXPECT
What should you expect, month by month?
- Week 1
Your protocol arrives. Start as directed and note how you feel.
- Month 1
Your body adjusts. Early changes, if any, are usually subtle; mild side effects often ease in this window.
- Month 3
Many patients begin to notice change. Your physician checks in and adjusts the dose if needed.
- Month 6+
Progress is reassessed with your physician, who decides whether to continue, adjust or taper.
Timelines vary by person, dose and condition. Your physician sets the pace and adjusts as you go.
FAQ
Common questions about Tretinoin Cream
Still deciding between strengths, or between this and another protocol?
Take the 60-second quiz
Am I eligible?
Eligibility is a clinical decision. After you check out, you'll complete a medical intake; a US-licensed physician reviews it and determines whether this protocol is appropriate for you. If it isn't, the hold on your card is released and you're not charged.
Is tretinoin compounded?
No. You receive FDA-approved generic tretinoin cream, in the strength your physician prescribes, from a US-licensed pharmacy.
How do I use it?
At night, apply a pea-sized amount to clean, dry skin. Many people start every other night and build up as their skin adjusts. Wear a broad-spectrum sunscreen every morning, because tretinoin makes skin more sensitive to the sun.
What side effects should I expect?
Dryness, peeling, redness and mild stinging are common in the first few weeks, and some people see a temporary flare before skin improves. Tell your physician if you are pregnant, planning a pregnancy, or breastfeeding.
Which strength is right for me?
Your physician chooses based on your skin and history, usually starting low and moving up only once your skin tolerates it.
How is it shipped?
Discreetly, in plain, unbranded packaging, straight from a US-licensed pharmacy. No special handling needed; store it as your pharmacy label directs.
What if I'm not approved?
You're not charged. Checkout places a temporary hold on your card, and it's released if a physician doesn't approve your protocol. Where possible, your physician may suggest an alternative that fits your case.
What's included, and what's billed separately?
Your price covers your physician review, your prescription, messaging with your care team and, for most protocols, your medication and shipping from a US-licensed pharmacy. Brand-name GLP-1 care is the exception: you buy the medication from the manufacturer's own pharmacy. For isotretinoin, the required lab work (blood tests, and monthly pregnancy tests if you can become pregnant) is billed separately by the lab.
How quickly will it arrive?
Once a physician approves your protocol, the pharmacy prepares your prescription and ships it to you. Your dashboard shows the status and tracking at every step.
Can I cancel or pause?
Yes, there's no lock-in. You can pause or cancel your protocol anytime from your dashboard before your next fulfilment.
Read: More acne answers

TRETINOIN CREAM · $99 / 3 MONTHS
Ready when you are.
Start your protocolCharged only if a physician approves you.